2-Methoxycinnamaldehyde Reduces IL-1.BETA.-Induced Prostaglandin Production in Rat Cerebral Endothelial Cells
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Acetaminophen-sensitive prostaglandin production in rat cerebral endothelial cells.
Acetaminophen is a widely used antipyretic and analgesic drug whose mechanism of action has recently been suggested to involve inhibitory effects on prostaglandin synthesis via a newly discovered cyclooxygenase variant (COX-3). Because COX-3 expression is high in cerebral endothelium, we investigated the effect of acetaminophen on the prostaglandin production of cultured rat cerebral endothelia...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2006
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.29.2214